Supporting the LCA Community

We see a cure for blindness

Baby with Leber Congenital Amaurosis
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Living with LCA

Since 2014, we’ve supported the LCA community with education, resources, and connections that strengthen and unite individuals and families across the IRD community.

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Get Involved

Our donors and corporate partners drive our mission, helping us impact lives of those with LCA and rare IRDs. Learn about events, sponsorships, and partnerships.

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Finding a Cure

By supporting the ecosystem that develops treatments for blinding diseases, we can advance therapies to approval. Join us in making these breakthroughs possible.

Episode 14 with Dr. Paul Yang

Episode 14 – The Latest in LCA1 and LCA4 Research with Dr. Paul Yang

In this episode, host Ben Shaberman, Science Communications Advisor to Hope in Focus, welcomes Dr. Paul Yang of the Casey Eye Institute at Oregon Health & Science University. A leading clinical researcher for inherited retinal diseases, Dr. Yang discusses promising results for clinical trials of LCA1 and LCA4 gene therapies, and how optogenetics shows potential […]

Opus Genetics Receives FDA Clearance for LCA13 Gene Therapy Trial

LCA13 (RDH12) Gene Therapy Poised to Move into Clinical Trial

Opus Genetics has received authorization from the US Food and Drug Administration (FDA) to launch a Phase 1/2 clinical trial for its emerging gene therapy for people with Leber congenital amaurosis 13 (LCA13) which is caused by mutations in the gene RDH12.  The company plans to enroll 10 people in the trial including adolescents (ages […]

A person taking a picture of the Dinner in the Dark sign

Dinner in the Dark

October 24, 2026 • Foxwoods Resort and Casino, Mashantucket, CT Our primary fundraiser for the year, this event is a true culinary adventure! You will enjoy a gourmet dinner while wearing a blindfold, and we keep the menu secret. Come learn about the exciting ways we are working to transform the lives of those without […]

27+

genetic mutations can cause LCA

$2.5M+

raised to support research and community programs

32+

countries in our global reach